The SPPL3-Defined Glycosphingolipid Repertoire Regulates Immune Responses by Improving HLA Class I Access
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چکیده
منابع مشابه
The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G.
Selective expression of the human class Ib HLA molecule HLA-G in immunologically protected sites and its function in the inhibition of NK and T-cell effector functions support an important role of this molecule in immunoregulation. Here, we demonstrate that HLA-G is constitutively expressed in the endocrine compartment of the human pancreas. Surface expression of this HLA determinant in endocri...
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ژورنال
عنوان ژورنال: SSRN Electronic Journal
سال: 2020
ISSN: 1556-5068
DOI: 10.2139/ssrn.3584519